2012
Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described hallmarks of Alzheimer’s disease, but their relationships are poorly (…)
Consulter
2013
(18)F-florbetaben and positron emission tomography were used to examine the relationships between β-amyloid (Aβ) deposition, cognition, hippocampal volume, and white (…)
Consulter
2013
The amyloid cascade hypothesis, which posits that amyloid-β accumulation is the key event in Alzheimer disease neurodegeneration, has dominated the (…)
Consulter
2013
Normal aging is characterized by brain glucose metabolism decline predominantly in the prefrontal cortex. The goal of the present study (…)
Consulter
2013
More educated elders are less susceptible to age-related or pathological cognitive changes. We aimed at providing a comprehensive contribution to (…)
Consulter
2013
Revised diagnostic criteria for Alzheimer disease (AD) acknowledge a key role of imaging biomarkers for early diagnosis. Diagnostic accuracy depends (…)
Consulter