2010
Although the molecular bases of its actions remain debated, tissue-type plasminogen activator (tPA) is a paradoxical brain protease, as it (…)
Consulter 
2010
Normal neuronal functioning is dependent on the blood-brain barrier. This barrier is confined to specialized brain endothelial cells lining the (…)
Consulter
2010
Despite its pro-fibrinolytic activity, tPA (tissue plasminogen activator) is a serine protease known to influence a number of physiological and (…)
Consulter
2010
Cell activation by stressors is characterized by a sequence of detectable phenotypic cell changes. A given stimulus, depending on its (…)
Consulter
2011
Consulter
2010
Despite its fibrinolytic effect, tissue-type plasminogen activator (tPA) displays deleterious effects in the brain, including proexcitotoxicity, that can reduce the (…)
Consulter
